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The reduced activity of antioxidant enzymes in the body results in DNA hydroxylation, protein denaturation, increased lipid peroxidation, and impairment of cellular functions, disrupting the conditions necessary for cell survival

An InChIKey is a simplified version of a full InChI, designed for easier web searching.Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al

This trial also looked at the more stringent composite response of minimal disease activity (MDA), met by 27% of the golimumab group at 14 weeks, compared with 4% of the placebo group

P., Hansson, C., Alvarez-Crespo, M., Friberg, P